By Adrienne Dellwo, Fibromyalgia & Chronic Fatigue Guide – Wednesday September 15, 2010
A small study just published in the online version of BMC Musculoskeletal Disorders shows that the drug trazodone may be an effective treatment for fibromyalgia. However, researchers warn of a serious side effect.
Researchers say trazodone made participants sleep better and longer, improved how they felt and functioned, and lessened their anxiety and depression. They also report tachycardia (rapid heart beat) in more than 20% of patients and recommend close monitoring. Tachycardia is a known side effect of this drug, but it surprised researchers by its frequency and severity in this study.
Trazodone is sold under the brand name Desyrel. It’s classified as an atypical antidepressant, but it has some factors in common with both tricyclics (such as amitriptyline or doxepin) and SSRIs (fluoxetine, paroxetine.) It’s a more effective sedative than other antidepressants and is often prescribed as a sleep aid. It also blocks some nerve transmissions.
In addition to tachycardia, side effects include:
- Feeling faint or lightheaded
- Sexual dysfunction, including painful erections
- Suicidal thoughts or other mood changes
- Muscle pain
- Nausea and vomiting
Get more information on this drug: Trazodone.